Saturday, August 18, 2018 | ePaper

Being young and overweight may change heart function

  • Print


Life Desk :
Being overweight at a young age may change the structure and functions of the heart, reports a new study. The findings of the study are published in the American Heart Association's journal Circulation.
A new study suggests overweight in young adults may cause higher blood pressure and thicken heart muscle, thereby increasing the risk of developing heart disease in later life.
'A person who is overweight or having a higher BMI (body mass index) at a younger age is more likely to have hypertension (high blood pressure) and changes in the structure and functions of the heart which may increase the risk of heart disease in later life.'
The study is the first to examine whether higher BMI (body mass index) which is a weight-for-height index may result in unfavorable outcomes on the cardiovascular system in young adults.
Previous observational studies can suggest associations between risk factors or lifestyle behaviors and heart disease, but they cannot prove the cause-and-effect. In the present study, a team of researchers triangulated the findings from three different types of genetic analysis to reveal evidence that BMI causes specific differences in cardiovascular measurements.
The results of the study can encourage efforts to reduce body mass index (BMI) to within a normal, healthy range from a young age to prevent the risk of developing heart disease in later life, said Kaitlin H. Wade, B.Sc., Ph.D., lead author of the study and a research associate at the Medical Research Council Integrative Epidemiology Unit at the University of Bristol Medical School in the United Kingdom.
Details of the study
The research team analyzed data on several thousand healthy 17 to 21-year-olds from Bristol, United Kingdom, who have participated in the Children of the 90s study and have been monitored since they were born.
Findings of the study
The findings of the study suggest that higher BMI caused:
higher systolic (upper value) and diastolic (lower value) blood pressure
enlargement of the heart's main pumping chamber, the left ventricle

"Thickening of vessel walls is widely considered to be the first sign of atherosclerosis, a disease in which fatty plaques build up within the arteries and lead to heart disease. However, our findings suggest that higher BMIs cause changes in the heart structure of the young that may precede changes in blood vessels," said Wade.
Mendelian randomization and recall-by-genotype are the two analyses used in the study take advantage of the properties of genetic variation. Recall-by-genotype is new and utilizes the random allocation of genes at conception.
"At a population level, this provides a natural experiment analogous to a randomized trial where we can compare differences in an outcome (such as heart structure and function) with differences in BMI, without the relationship being skewed by other lifestyle and behavioral factors," said Wade.
Limitations of the study
Most participants in the longitudinal studies were white, limiting the generalizability of the findings to other ethnic groups.
For further research, the team of researchers will plan to investigate the relationship between BMI and heart structure and function in a cohort in their 70s. They also hope to examine whether there is a correlation between higher BMI and other possible disease mechanisms such as the diversity of microbes in the gut.
Source: Medindia

More News For this Category

Benefits of steaming face

Benefits of steaming face

Life Desk :Facial steaming is a cost-saving and easy way to cleanse and improve the health of the skin. It is a simple skin care routine in which you allow

New cure for migraine

New cure for migraine

Life Desk  :The first drug to prevent migraine has been approved by European health officials. According to a report in The Guardian, the drug Erenumab will now be examined by

Can pineapples be used to heal wounds?

Can pineapples be used to heal wounds?

Life Desk :From Piña colada to the delectable yoghurts and fruit punches, pineapple adds a zest of flavour to food. While it is among one of the most famous tropical

Controlling cocaine abuse with elevated bile acid levels

Controlling cocaine abuse with elevated bile acid levels

Life Desk :Drug abuse can now be prevented with a new strategy involving bile acids. Bile acids that aid in fat digestion may reduce the rewarding properties of cocaine use,

Keep your heart healthy with 'Pistachios'

Keep your heart healthy with 'Pistachios'

Life Desk :Good things come in small packages and the same is applicable to nuts. Apart from being delicious, these bite-sized crunchy goodies have numerous health benefits. While there are

Salt consumption and the risk of heart attack

Salt consumption and the risk of heart attack

Dr. Lakshmi Venkataraman :Moderate sodium (common salt) ingestion less than 5 grams per day does not increase risk of heart attack or stroke according to a global studyMost communities

Visual patterns: Draw a House-Tree-Person

Visual patterns: Draw a House-Tree-Person

Robert Barkman, Ph.D  :That child's drawing of a house, tree, or person may represent more than an element of the refrigerator-as-art-gallery. It may predict a child's intelligence later in

Wedding that predicts a happy marriage

Wedding that predicts a happy marriage

Wendy L. Patrick, Ph.D : A marriage is a covenant relationship designed to last "till death do us part."  Accordingly, a couple planning a wedding is carefully designing a celebration

Cure for Twitter addiction

Cure for Twitter addiction

Steve Albrecht  :Same thing happened when Monica Lewinsky, Lou Diamond Phillips, Dan Harris, Adam Carolla, and Dr Drew retweeted something I wrote. I felt a physical buzz that bordered

Salt — a silent killer in your food

Salt — a silent killer in your food

Judith Wurtman  :A few months ago we dined with friends in a restaurant featuring small plates of 'interesting food' that were meant to be shared by everyone at the