Sunday, January 21, 2018 | ePaper

Male partner's age can affect IVF success

  • Print


Life Desk :
Discarding the idea that male fertility goes on forever, new research warns that the chances of having a baby through IVF may depend on the age of the male partner as well - not just the age of women. This study of almost 19,000 IVF treatment cycles showed a decline in the success rate with increasing male partner age.
"Our study found an independent effect of male age on the cumulative incidence of live birth," said investigator Laura Dodge from Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, US.
The study, scheduled to be presented at the European Society of Human Reproduction and Embryology meeting in Geneva on Tuesday, was an analysis of all IVF cycles performed at a large IVF centre in the Boston region between 2000 and 2014, a total of almost 19,000 cycles performed in 7,753 couples. The female partners in these cycles were stratified according to four age bands - under 30, 30-35 years, 35-40 years and 40-42. Men were stratified into these same four age bands, with an additional band of 42 and over. As expected, the cumulative live birth rate (measured from up to six cycles of treatment) was lowest in those couples where the female partner was in the 40-42 age band, and in this group the age of the male partner had no impact, demonstrating the dominant detrimental effect of female age.
However, within the other bands of female age, the cumulative incidence of live birth was significantly affected by male partner age and was found to decline as the man grew older. For example, in couples with a female partner aged under 30, a male partner aged 40-42 was associated with a significantly lower cumulative birth rate (46 per cent) than a male partner aged 30-35 (73 per cent).
Similarly, in couples with a female partner aged 35-40 years live birth rates were higher with a younger than with an older male partner. "Women aged 35-40 did significantly benefit from having a male partner who is under age 30, in that they see a nearly 30% relative improvement in cumulative incidence of live birth when compared to women whose partner is 30-35 - from 54 per cent to 70 per cent," Dodge said.
For women between ages 30 and 35, having a partner who is older than they are is associated with approximately 11 per cent relative decreases in cumulative incidence of live birth when compared with having a male partner within their same age band, Dodge said.
In natural conceptions increasing male age is associated with a decreased incidence of pregnancy, increased time to pregnancy, and increased risk of miscarriage, Dodge noted.
The mechanisms, she added, are unclear but may include impaired semen parameters, increased DNA damage in sperm, and epigenetic alterations in sperm that affect fertilisation, implantation, or embryo development.

-IANS

More News For this Category

Intermittent fasting : A key to good health

Intermittent fasting : A key to good health

Life Desk :Fasting has been known to mankind since ancient times. Almost all the religions across the globe endorse fasting as a means to achieve spiritual goals and wellbeing

Caffeine level in blood may predict Parkinson's disease

Life Desk  :The findings showed that people with Parkinson's disease had significantly lower levels of caffeine in their blood than people without the disease, even if they consumed the

Women who do night shifts may be at risk of cancer

Women who do night shifts may be at risk of cancer

Life Desk :Long-term night shift work in women was associated with risk for nearly a dozen types of cancer. Breast, skin, and gastrointestinal cancer was associated with night shift

How you look in a dress you are yet to buy

How you look in a dress you are yet to buy

Life Desk  :Amazon has patented a reality mirror that lets you try on clothes virtually while placing you in a virtual location.The patent describes the mirror as partially-reflective and

Working on mobile devices from home may affect family life

Working on mobile devices from home may affect family life

Life Desk  :Too much office workload? Do not bring it home as it might spoil intimacy with your partner and affect your professional life too, a new study has

Paracetamol in pregnancy may damage your daughter's fertility

Paracetamol in pregnancy may damage your daughter's fertility

Life Desk  :Women who consume paracetamol during pregnancy, widely used to reduce a high fever or relieve pain, may increase the risk of damaging the fertility of their daughters,

Gender-based colours in toys can spur harmful stereotypes

Gender-based colours in toys can spur harmful stereotypes

Life Desk :Do you tend to buy only pink toys for your daughter, while keeping the blue toys for your son? Buying gender-based colours for your children can actually

Be a bad mom in 2018!

Be a bad mom in 2018!

Life Desk  :You are a mom and can't fix a healthy wheat cupcake for your kid and her friends in a jiffy? Don't have the perfect yoga body and

Healthy lifestyle in winter

Healthy lifestyle in winter

Life Desk  :The onset of winters can prove to be a health hazard if you are not following a nutritious diet, and a balanced lifestyle. So make sure you

Sleeping less than 8 hours a night can lead to depression

Life Desk  :Regular sleep disruptions can increase the difficulty in shifting attention away from negative thoughts. While other people may be able to move on from their negative thoughts,